Natalizumab injection (Tysabri) — prior authorization under Cigna Healthcare
Billing code J2323 · Category: medications
In our reference, this procedure typically requires prior authorization.
Typical turnaround is 7 day(s); Cigna Healthcare's
standard turnaround is 14 calendar days (48 hours if urgent).
How to submit
Availity portal, Cigna for HCP portal, 800-768-4695
Documentation typically required
MS diagnosis docs
Prior treatment failure records
JC virus antibody test
Common reasons this gets denied
Step therapy not completed
JC virus risk not assessed
Cigna Healthcare-specific notes
eviCore for imaging and cardiology PA
Faster urgent turnaround (48h)
No PA for first 6 outpatient behavioral health visits on most plans
Coverage limits: this page does not confirm authorization for any specific member's plan, and does not cover state-specific plan variants, out-of-network requests, or every payer x procedure pair in existence. For a definitive answer, contact Cigna Healthcare directly using the submission method above.
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